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How PCOS Affects Fertility

Polycystic ovary syndrome (PCOS) is a common cause of infertility. This post explains how PCOS affects fertility, treatment options available in Dubai, and when to seek care at Zaincura.

Written by

Dr. Danish Sardar (M.D.)

Published

December 6, 2025

Reading time

5 min read

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How PCOS Affects Fertility

How PCOS Affects Fertility

If you have PCOS and are trying to start or expand your family, you may be asking: "How PCOS affect fertility?" You are not alone—PCOS (polycystic ovary syndrome) is a leading cause of infertility in women of reproductive age. This article explains how PCOS can interfere with conception, what treatments and lifestyle measures can help, and when to seek personalised care at Zaincura in Dubai. It's always best to consult a healthcare professional for a diagnosis. Our doctors at Zaincura can provide a personalized assessment.

Can I get pregnant with PCOS?

Yes — many women with PCOS can and do get pregnant. PCOS makes conception more difficult for some women, primarily because it commonly disrupts regular ovulation. However, with proper medical evaluation and treatment, the chances of pregnancy improve significantly. Treatments range from lifestyle changes and weight management to medication that induces ovulation, and assisted reproductive technologies when needed.

Key points to know:

  • PCOS is associated with irregular or absent periods, which often means irregular ovulation. Without regular ovulation, natural conception is less likely.
  • Insulin resistance and hormonal imbalances common in PCOS (higher androgens, altered LH/FSH ratio) can affect egg development and the uterine environment.
  • Fertility outcomes vary: some women conceive naturally, others need medical help; many achieve pregnancy with treatment.

How does PCOS affect fertility?

PCOS affects fertility through several interlinked mechanisms:

  • Irregular or absent ovulation (anovulation): Follicles may start to develop but not reach full maturity or release an egg, so there is no ovulation for fertilisation to occur.
  • Hormonal imbalance: Elevated androgens (male-type hormones) and altered gonadotropin secretion (LH/FSH imbalance) can impair follicle maturation.
  • Insulin resistance: Many women with PCOS have insulin resistance, which worsens hormonal disruption and may affect the quality of eggs and the uterine lining.
  • Endometrial effects: Irregular cycles can lead to thickened or less receptive endometrium, potentially reducing implantation success.
  • Associated conditions: Higher rates of obesity, metabolic syndrome, and inflammation in PCOS can indirectly reduce fertility and increase pregnancy risks.

Despite these challenges, fertility treatments can address many of the mechanisms above. It's always best to consult a healthcare professional for a diagnosis and personalised plan.

What are the common fertility treatments for PCOS?

Treatment is tailored to your symptoms, fertility goals, and overall health. Common options include:

  • Lifestyle changes: Weight management through diet, exercise, and behavioural support improves insulin sensitivity and can restore ovulation in many women with PCOS.
  • Ovulation induction medications: Drugs such as letrozole (often first-line), clomiphene citrate, or low-dose gonadotropins are used to stimulate ovulation.
  • Metformin: An insulin-sensitising medication that can help regulate cycles and, in combination with ovulation induction, may improve outcomes in some women.
  • Intrauterine insemination (IUI): Used when ovulation is induced but sperm factors or cervical issues exist.
  • In vitro fertilisation (IVF): Considered when other treatments fail or when there are additional fertility issues; IVF bypasses problems of ovulation and fertilisation.

Our doctors at Zaincura will recommend the safest, evidence-based approach for you. It's always best to consult a healthcare professional for a diagnosis.

Lifestyle and self-care recommendations

Many women with PCOS see improved fertility with targeted lifestyle changes:

  • Aim for gradual weight loss if overweight (5–10% can restore ovulation for many).
  • Follow a balanced diet rich in whole grains, lean proteins, healthy fats, fruits, and vegetables; consider referral to a dietitian.
  • Regular physical activity improves insulin sensitivity and overall health.
  • Manage stress and sleep, as both affect hormones and metabolic health.

These measures are part of comprehensive care and often complement medical treatments.

Fertility outlook and pregnancy considerations

With appropriate management, pregnancy rates for women with PCOS can be very encouraging. Women with PCOS may have higher risks during pregnancy (gestational diabetes, hypertensive disorders), so early prenatal care and metabolic monitoring are important. If you're planning pregnancy, preconception counselling and optimisation of weight, glucose control, and medications is recommended.

When to Visit a Doctor at Zaincura

You should consider booking an appointment at Zaincura if any of the following apply:

  • You have irregular or absent periods and are trying to conceive.
  • You have been trying to get pregnant for 6 months (if over age 35) or 12 months (if under 35) without success.
  • You have known PCOS and want personalised fertility planning or preconception care.
  • You experience other PCOS symptoms (excess facial/body hair, acne, rapid weight gain) alongside fertility concerns.

Our multidisciplinary team in Dubai offers endocrinology, gynaecology, reproductive medicine, and nutrition support. Our doctors at Zaincura can provide a personalized assessment and guide you through evidence-based options. It's always best to consult a healthcare professional for a diagnosis.

Conclusion

PCOS can make conceiving more challenging, but many women with PCOS achieve pregnancy with lifestyle changes, medical treatments, and assisted reproductive techniques when needed. Early assessment and a tailored treatment plan improve outcomes. If you suspect PCOS or are struggling to conceive, our team at Zaincura in Dubai is ready to help with compassionate, evidence-based care. It's always best to consult a healthcare professional for a diagnosis.

References

(Note: Links provided are to authoritative sources. For personalised diagnosis and treatment, please consult a healthcare professional. Our doctors at Zaincura can provide a personalized assessment.)

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About Dr. Danish Sardar (M.D.)

Dr. Danish Sardar (M.D.) is a healthcare professional at Zain Cura Medical Center, dedicated to providing expert medical advice and compassionate care to patients in Dubai.

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