PSA (prostate-specific antigen) is a protein produced by the prostate gland. Elevated PSA can indicate prostate cancer, benign prostatic hyperplasia (enlarged prostate), or prostatitis (inflammation). The PSA test is widely used for prostate cancer screening, though it's controversial due to false positives and overdiagnosis. PSA testing helps identify men at higher risk for prostate cancer who need further investigation. At Zain Cura Medical Center in Dubai, we perform accurate PSA testing with results in just 4-6 hours – no fasting required, walk-in welcome, and home collection available 24/7 across Dubai. Our DHA-licensed laboratory uses electrochemiluminescence immunoassay with 99.8% accuracy. PSA testing is an important tool for prostate health monitoring when used appropriately with shared decision-making.
Whether you're scheduling a routine health check or your doctor has recommended testing, understanding what this test measures and what your results mean is essential for informed health decisions.
Quick Facts
Essential information about the PSA (Prostate-Specific Antigen) test at a glance
What is a PSA Test?
A PSA test measures prostate-specific antigen, a protein produced by the prostate gland used for cancer screening and monitoring.
The prostate is a walnut-sized gland below the bladder that produces fluid component of semen and surrounds the urethra. PSA is made exclusively by prostate and present in blood in small amounts. Elevated levels may indicate disease, though levels commonly rise after digital rectal exam temporarily.
Prostate Cancer
Most concerning cause of elevation. Higher PSA correlates with cancer risk, though not all elevated PSA indicates cancer.
Benign Prostatic Hyperplasia (BPH)
Enlarged prostate very common in aging men. Causes urinary symptoms but not cancer. Can elevate PSA.
Prostatitis
Prostate inflammation or infection (acute or chronic) temporarily elevates PSA.
What Does This Test Detect?
Screening for prostate cancer; elevated in BPH and prostatitis
Why Your Doctor Orders This Test
The PSA (Prostate-Specific Antigen) is commonly ordered to screen for, diagnose, or monitor medical conditions. Your doctor may recommend this test as part of routine health screening, to investigate symptoms, or to track your response to treatment.
Why Get a PSA Test?
Prostate Cancer Screening
PSA helps identify men at higher risk for prostate cancer, allowing further investigation with biopsy if needed.
Monitoring Known Prostate Disease
Patients with diagnosed prostate cancer use PSA to monitor treatment response.
Evaluating Prostate Symptoms
Men with urinary symptoms may need PSA to evaluate prostate contribution.
Age-Based Screening
Older men benefit from baseline PSA for comparison over time and risk stratification.
When Should You Get This Test?
Consider getting tested if you have these symptoms or risk factors
Symptoms to Watch For
- •Difficulty urinating
- •Weak urine stream
- •Frequent urination
- •Urinary hesitancy
- •Incomplete emptying
- •Blood in urine
- •Painful urination
Risk Factors
- •Age 50+ (screening conversation recommended)
- •Age 40+ if family history of prostate cancer
- •African American ancestry (higher prostate cancer risk)
- •BRCA gene mutation
- •Family history of early prostate cancer
- •Elevated DRE findings
Recommended Testing Frequency
Screening discussion at 50, then annually if decided to screen
Baseline at 40-45, then annually
Per oncologist recommendations
Per treatment plan and oncologist
Normal Reference Ranges
These ranges are general guidelines. Your results should be interpreted by your doctor in the context of your individual health status and medical history.
Important: Normal ranges may vary based on age, sex, and individual factors. Always consult your healthcare provider for personalized interpretation of your results.
How to Prepare for Your Test
Follow these simple preparation guidelines for accurate results
Pre-Test Preparation
No ejaculation 48 hours before test. No rectal exam 48 hours before
What to Do
- • Bring valid ID (Emirates ID, passport, or driver's license)
- • Wear comfortable, short-sleeved clothing
- • Stay hydrated (drink water before test)
- • Arrive 10 minutes early for check-in
- • List current medications and supplements
What to Avoid
- • Excessive caffeine immediately before
- • Strenuous exercise 24 hours before
- • Don't skip prescribed medications without consulting doctor
- • Avoid stress and anxiety before blood draw
Related Laboratory Tests
Tests often ordered together for comprehensive health assessment
CA-125
Ovarian cancer marker; elevated in various malignancies
AFP (Alpha-Fetoprotein)
Liver and testicular cancer marker
CEA (Carcinoembryonic Antigen)
Colorectal cancer marker; elevated in various solid tumors
Complete Blood Count (CBC – 28 parameters)
Comprehensive analysis of red blood cells, white blood cells, platelets, hemoglobin, and hematocrit levels
Frequently Asked Questions
Common questions about the PSA (Prostate-Specific Antigen) test
Should I Get PSA Screening?
Controversial. Recommended for shared decision-making at age 50 (40-45 if higher risk). Benefits and risks should be discussed with doctor.
Do I Need Fasting for PSA?
No, fasting is not required. You can eat and drink normally. Results not affected by fasting.
When Should I Retest PSA?
Depends on initial result. Normal: every 1-2 years. Elevated: may need retesting in weeks to months, or additional testing. Doctor determines schedule.
Can Ejaculation Affect PSA?
Yes. Avoid ejaculation 2 days before testing. Can temporarily raise PSA levels.
Does DRE Affect PSA?
Yes. Avoid PSA testing within 3 days of digital rectal exam. Can transiently elevate PSA.
Is PSA Test Painful?
No. It's just a regular blood draw – small needle prick like a mosquito bite. No more uncomfortable than standard blood tests.
Can I Get PSA Test at Home?
Yes! Home collection is available 24/7 across Dubai. Same accuracy as clinic. Book via smart assistant chatbot.
If PSA is Elevated, Do I Have Cancer?
Not necessarily. Elevated PSA has 25% cancer probability in 4-10 range. Further testing needed to confirm. Many have benign conditions.
What's the Difference Between Total PSA and Free PSA?
Total PSA includes all PSA. Free PSA is unbound. Higher free PSA % indicates lower cancer probability. Used to refine risk if total PSA elevated.
Do I Need Insurance for PSA Testing?
No. Testing available without insurance. Affordable pricing at AED 99-149.
Recommended Test Packages
- PSA
- Free PSA %
- Testosterone
- DRE
- Ultrasound